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%ما هو (من)٪ 1 - تعريف

CLASS OF ENZYMES

Endolysin; Lysins; Endolysins; Murein hydrolase; Murein hydrolases; Phage lysin

lysin

['l??s?n]

¦ noun Biology an antibody or other substance able to cause lysis of cells (especially bacteria).

LysM domain

INTERPRO DOMAIN

User:Alexbateman/LysM domain; Lysin motif; Lysin Motif

In molecular biology the LysM domain is a protein domain found in a wide variety of extracellular proteins and receptors. The LysM domain is named after the Lysin Motif which was the original name given to the sequence motif identified in bacterial proteins.

https://en.wikipedia.org/wiki/LysM_domain

GNLY

PROTEIN-CODING GENE IN THE SPECIES HOMO SAPIENS

Granulysin; GNLY (gene); NK-lysin

Granulysin (GNLY) is a protein expressed in most mammals which functions as an antimicrobial peptide released by killer lymphocytes in cytotoxic granules. It is a pore-forming peptide, as it can puncture a microbial cell wall, allowing for other death-inducing enzymes to enter the microbe and cause microptosis.

https://en.wikipedia.org/wiki/GNLY

ويكيبيديا

Lysin

Lysins, also known as endolysins or murein hydrolases, are hydrolytic enzymes produced by bacteriophages in order to cleave the host's cell wall during the final stage of the lytic cycle. Lysins are highly evolved enzymes that are able to target one of the five bonds in peptidoglycan (murein), the main component of bacterial cell walls, which allows the release of progeny virions from the lysed cell. Cell-wall-containing Archaea are also lysed by specialized pseudomurein-cleaving lysins, while most archaeal viruses employ alternative mechanisms. Similarly, not all bacteriophages synthesize lysins: some small single-stranded DNA and RNA phages produce membrane proteins that activate the host's autolytic mechanisms such as autolysins.

Lysins are being used as antibacterial agents due to their high effectiveness and specificity in comparison with antibiotics, which are susceptible to bacterial resistance.

https://en.wikipedia.org/wiki/Lysin